Season 1Laura Linney stars in her Golden Globe®-winning role as Cathy Jamison, a 42-year-old schoolteacher who has always played by the rules. That is, until she receives a life-changing diagnosis. But instead of giving up Cathy decides to live it up! Also starring Oliver Platt (TV’s “Huff”) and Gabourey Sidibe (Precious). Season 2 Laura Linney returns in her Golden Globe®-winning role as Cathy Jamison in “The Big C.” Following the medical diagnosis that rocked her safe world, Cathy finally shares the news with her family and decides to pursue experimental treatment. She quickly bonds with her fellow patient, Lee (Hugh Dancy) – and his wine collection – but isn’t so sure about her new doctor (Alan Alda). Seasion 3Cathy's cancer goes into remission and she gets a new lease on life, toying with an alternate secret identity and trying to adopt a baby.Season 4 We've come full circle with Cathy's story – from her desire to live life to the fullest, to her realization that she's never felt more alive. Now more than ever, with her friends and family at her side, Cathy is up to the challenge of living every day as if it were her last.

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